Ultra Flora GI Regulate 150g- Metagenics

Specialised Probiotics And Prebiotic For Healthy Bowel Function

• Helps to support healthy bowel function.
• Reduce constipation and irritable bowel syndrome (IBS) symptoms via modulation of small intestinal bacterial overgrowth (SIBO), methane levels, SCFAs (i.e. butyrate), intestinal barrier integrity and inflammation.
• Low reactive, FODMAP free, powdered prebiotic and probiotic food for sensitive patients.

Benefits

Reduction of chronic constipation and IBS symptoms: Both IBS and non IBS related constipation are commonly occurring health issues in Australia, however, non IBS related constipation is twice as common in Australia as IBS. Lactobacillus plantarum 299v is extensively researched and shown to reduce a range of IBS symptoms. PHGG is a selective prebiotic, used as a fuel by butyrate producing bacteria. A meta-analysis of seven randomised trials of PHGG found a reduction in chronic constipation (Figure 1) while several randomised trials, found a significant decrease in IBS symptoms.

SIBO, methane and butyrate regulation; PHGG is fermented by large intestinal commensal bacteria increasing SCFA production particularly butyrate (Figure 2), as well as assisting colonic blood flow and epithelial repair. PHGG influences gut motility, secretions and vagal modulation of contraction, and has been shown to reduce methane levels. Methane production is implicated in the reduction in 5HT (gut serotonin) levels and reduced intestinal motility. Excessive production of methane has been linked to gastrointestinal issues such as SIBO, chronic constipation, IBS and slow transit time. PHGG may therefore assist in reducing severity of these conditions and symptoms.

Research of PHGG has also shown other benefits, including:

• Reduced methane excretion
• Improved effectiveness of antibiotic SIBO treatment (when used with PHGG)
• Improvements in chronic constipation

Visceral hypersensitivity, abdominal pain and inflammation; Probiotics can help modulate visceral hypersensitivity (increased pain sensitivity) to reduce abdominal pain and improve patient comfort. Both L. plantarum 299v and PHGG have been shown to reduce abdominal pain by 50%, which can be a key symptom driving patients to seek health advice. Gut inflammation can also contribute to pain and associated symptoms that may benefit from probiotic strains, such as L. plantarum 299v, shown to exert a modulatory effect on the inflammatory response of epithelium, helping to improve gastrointestinal comfort and health.

Directions / Serving suggestion:

Adults: Add 2 1/2 metric teaspoons (5 g) to 200 mL of water and stir until dissolved. Take once daily.

Ultra Flora GI Regulate is an easily dissolved and non-flavoured powder, making it suitable for mixing with other powdered supplements.

Store at 2°C to 8°C (Refrigerate. Do not freeze).